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ApoA Monoclonal Antibody

商品貨號： PLA004633

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： LPA
蛋白名稱： Apolipoprotein(a)
Human_gene_id： 4018
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4018
Human_swiss_prot_no： P08519
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08519/entry
特異性： ApoA Monoclonal Antibody detects endogenous levels of ApoA protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LPA; Apolipoprotein(a; Apo(a); Lp(a)
功能： disease:Elevated plasma concentrations of apo(a) and its naturally occurring proteolytic fragments are correlated with atherosclerosis. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.,function:Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.,miscellaneous:Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-Lp(a). Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation.,online information:The Singapore human mutation and polymorphism database,polymorphism:The genome version encodes a variant that contains 16 Kringle domains and that lack residues 533 to 3040.,PTM:N- and O-glycosylated. The N-glycans are complex biantennary structures present in either a mono- or disialylated state. The O-glycans are mostly (80%) represented by the monosialylated core type I structure, NeuNAcalpha2-3Galbeta1-3GalNAc, with smaller amounts of disialylated and non-sialylated O-glycans also detected.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Plasminogen subfamily.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 38 kringle domains.,subunit:Disulfide-linked to apo-B100. Binds to fibronectin and decorin.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： extracellular region,plasma lipoprotein particle,
組織表達(dá)： Liver,
科研貨號： PLA004633

ApoA Monoclonal Antibody

Catalog No PLA004633

Product information

發(fā)貨日期： 7
基因名稱： LPA
蛋白名稱： Apolipoprotein(a)
Human_gene_id： 4018
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4018
Human_swiss_prot_no： P08519
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08519/entry
特異性： ApoA Monoclonal Antibody detects endogenous levels of ApoA protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LPA; Apolipoprotein(a; Apo(a); Lp(a)
功能： disease:Elevated plasma concentrations of apo(a) and its naturally occurring proteolytic fragments are correlated with atherosclerosis. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.,function:Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.,miscellaneous:Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-Lp(a). Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation.,online information:The Singapore human mutation and polymorphism database,polymorphism:The genome version encodes a variant that contains 16 Kringle domains and that lack residues 533 to 3040.,PTM:N- and O-glycosylated. The N-glycans are complex biantennary structures present in either a mono- or disialylated state. The O-glycans are mostly (80%) represented by the monosialylated core type I structure, NeuNAcalpha2-3Galbeta1-3GalNAc, with smaller amounts of disialylated and non-sialylated O-glycans also detected.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Plasminogen subfamily.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 38 kringle domains.,subunit:Disulfide-linked to apo-B100. Binds to fibronectin and decorin.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： extracellular region,plasma lipoprotein particle,
組織表達(dá)： Liver,
科研貨號： PLA004633

Hunan UPT Biotechnology Co.,Ltd

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