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Arg Monoclonal Antibody

商品貨號(hào)： PLA004647

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

在線(xiàn)咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱(chēng)： ABL2
蛋白名稱(chēng)： Tyrosine-protein kinase ABL2
Human_gene_id： 27
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27
Human_swiss_prot_no： P42684
Human_swiss_link： http://www.uniprot.org/uniprotkb/P42684/entry
Mouse_swiss_prot_no： Q4JIM5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q4JIM5
特異性： Arg Monoclonal Antibody detects endogenous levels of Arg protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： ABL2; ABLL; ARG; Abelson tyrosine-protein kinase 2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; Tyrosine-protein kinase ARG
信號(hào)通路： ErbB_HER;Viral myocarditis;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,cofactor:Magnesium or manganese.,enzyme regulation:Stabilized in the inactive form by an association between the SH3 domain and the SH2-TK linker region, interactions of the amino-terminal cap, and contributions from an amino-terminal myristoyl group and phospholipids. Activated by autophosphorylation as well as by SRC-family kinase-mediated phosphorylation. Activated by RIN1 binding to the SH2 and SH3 domains. Inhibited by imatinib mesylate (Gleevec) which is used for the treatment of chronic myeloid leukemia (CML).,function:Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Widely expressed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm, cytoskeleton.
組織表達(dá)： Widely expressed.
科研貨號(hào)： PLA004647

Arg Monoclonal Antibody

Catalog No PLA004647

Product information

發(fā)貨日期： 7
基因名稱(chēng)： ABL2
蛋白名稱(chēng)： Tyrosine-protein kinase ABL2
Human_gene_id： 27
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27
Human_swiss_prot_no： P42684
Human_swiss_link： http://www.uniprot.org/uniprotkb/P42684/entry
Mouse_swiss_prot_no： Q4JIM5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q4JIM5
特異性： Arg Monoclonal Antibody detects endogenous levels of Arg protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： ABL2; ABLL; ARG; Abelson tyrosine-protein kinase 2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; Tyrosine-protein kinase ARG
信號(hào)通路： ErbB_HER;Viral myocarditis;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,cofactor:Magnesium or manganese.,enzyme regulation:Stabilized in the inactive form by an association between the SH3 domain and the SH2-TK linker region, interactions of the amino-terminal cap, and contributions from an amino-terminal myristoyl group and phospholipids. Activated by autophosphorylation as well as by SRC-family kinase-mediated phosphorylation. Activated by RIN1 binding to the SH2 and SH3 domains. Inhibited by imatinib mesylate (Gleevec) which is used for the treatment of chronic myeloid leukemia (CML).,function:Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Widely expressed.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm, cytoskeleton.
組織表達(dá)： Widely expressed.
科研貨號(hào)： PLA004647

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