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CD20 Monoclonal Antibody

商品貨號(hào)： PLA004702

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱： MS4A1
蛋白名稱： B-lymphocyte antigen CD20
Human_gene_id： 931
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=931
Human_swiss_prot_no： P11836
Human_swiss_link： http://www.uniprot.org/uniprotkb/P11836/entry
Mouse_swiss_prot_no： P19437
Mouse_swiss_link： http://www.uniprot.org/uniprot/P19437
特異性： CD20 Monoclonal Antibody detects endogenous levels of CD20 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： MS4A1; CD20; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD antigen CD20
信號(hào)通路： Hematopoietic cell lineage;
功能： caution:Epitope 1, mapped in PubMed:16785532, is predicted to be buried in the membrane. Its accessibility to the extracellular space, and thus to antibody recognition, is not explained.,function:This protein may be involved in the regulation of B-cell activation and proliferation.,online information:CD20 entry,pharmaceutical:Monoclonal antibodies(mAb) against CD20 are used to treat B-cell non-Hodgkin's lymphoma (NHL). These antibodies include Rituximab (Mabthera), Britumomab (Zevalin) and Tositumomab (Bexxar). CD20 engaged by mAb can generate transmembrane signals capable of directly controlling cell growth and triggering cell death in certain tumors. Alternatively, mAb can mediate complement-dependent cytotoxicity.,PTM:Phosphorylated. Might be functionally regulated by protein kinase(s).,similarity:Belongs to the MS4A family.,tissue specificity:Expressed on B-cells.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Multi-pass membrane protein . Cell membrane ; Lipid-anchor . Constitutively associated with membrane rafts. .
組織表達(dá)： Expressed on B-cells.
科研貨號(hào)： PLA004702

CD20 Monoclonal Antibody

Catalog No PLA004702

Product information

發(fā)貨日期： 7
基因名稱： MS4A1
蛋白名稱： B-lymphocyte antigen CD20
Human_gene_id： 931
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=931
Human_swiss_prot_no： P11836
Human_swiss_link： http://www.uniprot.org/uniprotkb/P11836/entry
Mouse_swiss_prot_no： P19437
Mouse_swiss_link： http://www.uniprot.org/uniprot/P19437
特異性： CD20 Monoclonal Antibody detects endogenous levels of CD20 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： MS4A1; CD20; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD antigen CD20
信號(hào)通路： Hematopoietic cell lineage;
功能： caution:Epitope 1, mapped in PubMed:16785532, is predicted to be buried in the membrane. Its accessibility to the extracellular space, and thus to antibody recognition, is not explained.,function:This protein may be involved in the regulation of B-cell activation and proliferation.,online information:CD20 entry,pharmaceutical:Monoclonal antibodies(mAb) against CD20 are used to treat B-cell non-Hodgkin's lymphoma (NHL). These antibodies include Rituximab (Mabthera), Britumomab (Zevalin) and Tositumomab (Bexxar). CD20 engaged by mAb can generate transmembrane signals capable of directly controlling cell growth and triggering cell death in certain tumors. Alternatively, mAb can mediate complement-dependent cytotoxicity.,PTM:Phosphorylated. Might be functionally regulated by protein kinase(s).,similarity:Belongs to the MS4A family.,tissue specificity:Expressed on B-cells.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Multi-pass membrane protein . Cell membrane ; Lipid-anchor . Constitutively associated with membrane rafts. .
組織表達(dá)： Expressed on B-cells.
科研貨號(hào)： PLA004702

Hunan UPT Biotechnology Co.,Ltd

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