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首頁(yè) > 抗體 > 一抗 > 其它 > Cdk1 Monoclonal Antibody
Cdk1 Monoclonal Antibody
商品貨號(hào): PLA004724
適 應(yīng) 性: 人,小鼠,大鼠,猴
WB ELISA
¥600元
規(guī)格:
在線咨詢
MSDS
說明書
商品描述
  • 發(fā)貨日期: 7
  • 基因名稱: CDK1
  • 蛋白名稱: Cell division protein kinase 1
  • Human_gene_id: 983
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=983
  • Human_swiss_prot_no: P06493
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P06493/entry
  • Mouse_gene_id: 12534
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12534
  • Mouse_swiss_prot_no: P11440
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P11440
  • Rat_gene_id: 54237
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54237
  • Rat_swiss_prot_no: P39951
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P39951
  • 特異性: Cdk1 Monoclonal Antibody detects endogenous levels of Cdk1 protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase
  • 信號(hào)通路: Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;Oocyte meiosis;p53;Gap junction;Progesterone-mediated oocyte maturation;
  • 功能: catalytic activity:ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Phosphorylation at Thr-14 or Tyr-15 inactivates the enzyme, while phosphorylation at Thr-161 activates it.,function:Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with DLGAP5. Isoform 2 is unable to complex with cyclin B1 and also fails to bind to the CDK inhibitor p21. Interacts with catalytically active CCNB1 and RALBP1 during mitosis to form an endocytotic complex during interphase.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus. Cytoplasm. Mitochondrion . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle. Cytoplasmic during the interphase. Colocalizes with SIRT2 on centrosome during prophase and on splindle fibers during metaphase of the mitotic cell cycle. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.
  • 組織表達(dá): Isoform 2 is found in breast cancer tissues.
  • 科研貨號(hào): PLA004724
Cdk1 Monoclonal Antibody
Catalog No PLA004724
Product information
  • 發(fā)貨日期: 7
  • 基因名稱: CDK1
  • 蛋白名稱: Cell division protein kinase 1
  • Human_gene_id: 983
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=983
  • Human_swiss_prot_no: P06493
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P06493/entry
  • Mouse_gene_id: 12534
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12534
  • Mouse_swiss_prot_no: P11440
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P11440
  • Rat_gene_id: 54237
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54237
  • Rat_swiss_prot_no: P39951
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P39951
  • 特異性: Cdk1 Monoclonal Antibody detects endogenous levels of Cdk1 protein.
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Monoclonal, Mouse
  • 稀釋: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 純化工藝: Affinity purification
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名稱: CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase
  • 信號(hào)通路: Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;Oocyte meiosis;p53;Gap junction;Progesterone-mediated oocyte maturation;
  • 功能: catalytic activity:ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Phosphorylation at Thr-14 or Tyr-15 inactivates the enzyme, while phosphorylation at Thr-161 activates it.,function:Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with DLGAP5. Isoform 2 is unable to complex with cyclin B1 and also fails to bind to the CDK inhibitor p21. Interacts with catalytically active CCNB1 and RALBP1 during mitosis to form an endocytotic complex during interphase.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus. Cytoplasm. Mitochondrion . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle. Cytoplasmic during the interphase. Colocalizes with SIRT2 on centrosome during prophase and on splindle fibers during metaphase of the mitotic cell cycle. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.
  • 組織表達(dá): Isoform 2 is found in breast cancer tissues.
  • 科研貨號(hào): PLA004724
  • Hunan UPT Biotechnology Co.,Ltd
    Website:m.jx3dscan.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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