欧美高清视频一区二区三区5,国产超碰在线免费观看

> > > >

Elk1 Monoclonal Antibody

商品貨號(hào)： PLA004767

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢

MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： ELK1
蛋白名稱： ETS domain-containing protein Elk-1
Human_gene_id： 2002
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2002
Human_swiss_prot_no： P19419
Human_swiss_link： http://www.uniprot.org/uniprotkb/P19419/entry
Mouse_swiss_prot_no： P41969
Mouse_swiss_link： http://www.uniprot.org/uniprot/P41969
特異性： Elk1 Monoclonal Antibody detects endogenous levels of Elk1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： ELK1; ETS domain-containing protein Elk-1
信號(hào)通路： MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Focal adhesion;Insulin_Receptor;GnRH;Prion diseases;Endometrial cancer;
功能： function:Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element.,PTM:On mitogenic stimulation, phosphorylated on C-terminal serine and threonine residues by MAPK1. Ser-383 and Ser-389 are the preferred sites for MAPK1. In vitro, phosphorylation by MAPK1 potentiates ternary complex formation with the serum responses factors, SRE and SRF. Phosphorylation leads to loss of sumoylation and restores transcriptional activator activity.,PTM:Sumoylation represses transcriptional activator activity as it results in recruitment of HDAC2 to target gene promoters which leads to decreased histone acetylation and reduced transactivator activity. It also regulates nuclear retention.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Interacts in its sumoylated form with PIAS2/PIASX which enhances its transcriptional activator activity.,tissue specificity:Lung and testis.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus.
組織表達(dá)： Lung and testis.
科研貨號(hào)： PLA004767

Elk1 Monoclonal Antibody

Catalog No PLA004767

Product information

發(fā)貨日期： 7
基因名稱： ELK1
蛋白名稱： ETS domain-containing protein Elk-1
Human_gene_id： 2002
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2002
Human_swiss_prot_no： P19419
Human_swiss_link： http://www.uniprot.org/uniprotkb/P19419/entry
Mouse_swiss_prot_no： P41969
Mouse_swiss_link： http://www.uniprot.org/uniprot/P41969
特異性： Elk1 Monoclonal Antibody detects endogenous levels of Elk1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： ELK1; ETS domain-containing protein Elk-1
信號(hào)通路： MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Focal adhesion;Insulin_Receptor;GnRH;Prion diseases;Endometrial cancer;
功能： function:Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element.,PTM:On mitogenic stimulation, phosphorylated on C-terminal serine and threonine residues by MAPK1. Ser-383 and Ser-389 are the preferred sites for MAPK1. In vitro, phosphorylation by MAPK1 potentiates ternary complex formation with the serum responses factors, SRE and SRF. Phosphorylation leads to loss of sumoylation and restores transcriptional activator activity.,PTM:Sumoylation represses transcriptional activator activity as it results in recruitment of HDAC2 to target gene promoters which leads to decreased histone acetylation and reduced transactivator activity. It also regulates nuclear retention.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Interacts in its sumoylated form with PIAS2/PIASX which enhances its transcriptional activator activity.,tissue specificity:Lung and testis.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus.
組織表達(dá)： Lung and testis.
科研貨號(hào)： PLA004767

Hunan UPT Biotechnology Co.,Ltd

Website：m.jx3dscan.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.