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FGFR-4 Monoclonal Antibody

商品貨號(hào)： PLA004802

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書

商品描述

發(fā)貨日期： 7
基因名稱： FGFR4
蛋白名稱： Fibroblast growth factor receptor 4
Human_gene_id： 2264
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2264
Human_swiss_prot_no： P22455
Human_swiss_link： http://www.uniprot.org/uniprotkb/P22455/entry
Mouse_swiss_prot_no： Q03142
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q03142
特異性： FGFR-4 Monoclonal Antibody detects endogenous levels of FGFR-4 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： FGFR4; JTK2; TKF; Fibroblast growth factor receptor 4; FGFR-4; CD antigen CD334
信號(hào)通路： MAPK_ERK_Growth;MAPK_G_Protein;Endocytosis;Regulates Actin and Cytoskeleton;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.,PTM:Glycosylated (By similarity). Phosphorylated on tyrosine residue (By similarity). Phosphorylation requires the presence of a functional (phosphorylated) FGFR1 and not necessarily by means of FGFR heterodimerization.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Isoform 2 may be secreted.,subunit:Interacts with KLB.,tissue specificity:Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane; Single-pass type I membrane protein. Endosome. Endoplasmic reticulum. Internalized from the cell membrane to recycling endosomes, and from there back to the cell membrane.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm .
組織表達(dá)： Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.
科研貨號(hào)： PLA004802

FGFR-4 Monoclonal Antibody

Catalog No PLA004802

Product information

發(fā)貨日期： 7
基因名稱： FGFR4
蛋白名稱： Fibroblast growth factor receptor 4
Human_gene_id： 2264
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2264
Human_swiss_prot_no： P22455
Human_swiss_link： http://www.uniprot.org/uniprotkb/P22455/entry
Mouse_swiss_prot_no： Q03142
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q03142
特異性： FGFR-4 Monoclonal Antibody detects endogenous levels of FGFR-4 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： FGFR4; JTK2; TKF; Fibroblast growth factor receptor 4; FGFR-4; CD antigen CD334
信號(hào)通路： MAPK_ERK_Growth;MAPK_G_Protein;Endocytosis;Regulates Actin and Cytoskeleton;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.,PTM:Glycosylated (By similarity). Phosphorylated on tyrosine residue (By similarity). Phosphorylation requires the presence of a functional (phosphorylated) FGFR1 and not necessarily by means of FGFR heterodimerization.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Isoform 2 may be secreted.,subunit:Interacts with KLB.,tissue specificity:Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane; Single-pass type I membrane protein. Endosome. Endoplasmic reticulum. Internalized from the cell membrane to recycling endosomes, and from there back to the cell membrane.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm .
組織表達(dá)： Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.
科研貨號(hào)： PLA004802

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