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FoxD3 Monoclonal Antibody

商品貨號(hào)： PLA004814

適應(yīng) 性： 人,小鼠,猴

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱(chēng)： FOXD3
蛋白名稱(chēng)： Forkhead box protein D3
Human_gene_id： 27022
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27022
Human_swiss_prot_no： Q9UJU5
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UJU5/entry
Mouse_gene_id： 15221
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15221
Mouse_swiss_prot_no： Q61060
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61060
特異性： FoxD3 Monoclonal Antibody detects endogenous levels of FoxD3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： FOXD3; HFH2; Forkhead box protein D3; HNF3/FH transcription factor genesis
功能： disease:Defects in FOXD3 are associated with susceptibility to autoimmune disease type 1 (AIS1) [MIM:607836]; also called vitiligo-associated multiple autoimmune disease susceptibility type 2 (VAMAS2). Generalized vitiligo is an acquired disorder in which white patches of skin and hair result from autoimmune loss of melanocytes, often associated with other autoimmune disorders. Most cases occur in a sporadic family pattern suggesting polygenic, multifactorial inheritance. However, a striking family in which a somewhat unusual vitiligo phenotype has been described, characterized by progressively coalescent diffuse depigmentation and relatively early disease onset, segregated as an apparent autosomal dominant with incomplete penetrance.,function:Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.
科研貨號(hào)： PLA004814

FoxD3 Monoclonal Antibody

Catalog No PLA004814

Product information

發(fā)貨日期： 7
基因名稱(chēng)： FOXD3
蛋白名稱(chēng)： Forkhead box protein D3
Human_gene_id： 27022
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27022
Human_swiss_prot_no： Q9UJU5
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UJU5/entry
Mouse_gene_id： 15221
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15221
Mouse_swiss_prot_no： Q61060
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61060
特異性： FoxD3 Monoclonal Antibody detects endogenous levels of FoxD3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： FOXD3; HFH2; Forkhead box protein D3; HNF3/FH transcription factor genesis
功能： disease:Defects in FOXD3 are associated with susceptibility to autoimmune disease type 1 (AIS1) [MIM:607836]; also called vitiligo-associated multiple autoimmune disease susceptibility type 2 (VAMAS2). Generalized vitiligo is an acquired disorder in which white patches of skin and hair result from autoimmune loss of melanocytes, often associated with other autoimmune disorders. Most cases occur in a sporadic family pattern suggesting polygenic, multifactorial inheritance. However, a striking family in which a somewhat unusual vitiligo phenotype has been described, characterized by progressively coalescent diffuse depigmentation and relatively early disease onset, segregated as an apparent autosomal dominant with incomplete penetrance.,function:Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus .
組織表達(dá)： Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.
科研貨號(hào)： PLA004814

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