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IL-6 Monoclonal Antibody

商品貨號(hào)： PLA004877

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： IL6
蛋白名稱： Interleukin-6
Human_gene_id： 3569
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3569
Human_swiss_prot_no： P05231
Human_swiss_link： http://www.uniprot.org/uniprotkb/P05231/entry
Mouse_swiss_prot_no： P08505
Mouse_swiss_link： http://www.uniprot.org/uniprot/P08505
特異性： IL-6 Monoclonal Antibody detects endogenous levels of IL-6 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： IL6; IFNB2; Interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
信號(hào)通路： Cytokine-cytokine receptor interaction;Toll_Like;NOD-like receptor;Cytosolic DNA-sensing pathway;Jak_STAT;Hematopoietic cell lineage;Intestinal immune network for IgA production;Prion diseases;Pathways in cancer;Graft-versus-host disease;Hypertrophic cardiomyopathy (HCM);
功能： disease:At least 1 polymorphism in the IL6 gene renders HIV-infected men susceptible to Kaposi sarcoma [MIM:148000]. Kaposi sarcoma is a sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumor that results in multifocal purplish coloured papules or plaques that eventually form nodules. Most commonly seen in patients who suffer from AIDS.,disease:Genetic variations in IL6 are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe, debilitating, extraarticular features, and occasionally fatal complications. Despite medical treatment, many children still experience early joint destruction, necessitating surgical replacement.,function:IL-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants.,online information:Interleukin-6 entry,online information:The Singapore human mutation and polymorphism database,polymorphism:Genetic variations in IL6 may be correlated with bone mineral density (BMD). Low BMD is a risk factor for osteoporotic fracture. Osteoporosis is characterized by reduced bone mineral density, disrutption of bone microarchitecture, and the alteration of the amount and variety of non-collagenous proteins in bone. Osteoporotic bones are more at risk of fracture.,PTM:N- and O-glycosylated.,similarity:Belongs to the IL-6 superfamily.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted .
組織表達(dá)： Produced by skeletal muscle.
科研貨號(hào)： PLA004877

IL-6 Monoclonal Antibody

Catalog No PLA004877

Product information

發(fā)貨日期： 7
基因名稱： IL6
蛋白名稱： Interleukin-6
Human_gene_id： 3569
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3569
Human_swiss_prot_no： P05231
Human_swiss_link： http://www.uniprot.org/uniprotkb/P05231/entry
Mouse_swiss_prot_no： P08505
Mouse_swiss_link： http://www.uniprot.org/uniprot/P08505
特異性： IL-6 Monoclonal Antibody detects endogenous levels of IL-6 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： IL6; IFNB2; Interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
信號(hào)通路： Cytokine-cytokine receptor interaction;Toll_Like;NOD-like receptor;Cytosolic DNA-sensing pathway;Jak_STAT;Hematopoietic cell lineage;Intestinal immune network for IgA production;Prion diseases;Pathways in cancer;Graft-versus-host disease;Hypertrophic cardiomyopathy (HCM);
功能： disease:At least 1 polymorphism in the IL6 gene renders HIV-infected men susceptible to Kaposi sarcoma [MIM:148000]. Kaposi sarcoma is a sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumor that results in multifocal purplish coloured papules or plaques that eventually form nodules. Most commonly seen in patients who suffer from AIDS.,disease:Genetic variations in IL6 are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe, debilitating, extraarticular features, and occasionally fatal complications. Despite medical treatment, many children still experience early joint destruction, necessitating surgical replacement.,function:IL-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants.,online information:Interleukin-6 entry,online information:The Singapore human mutation and polymorphism database,polymorphism:Genetic variations in IL6 may be correlated with bone mineral density (BMD). Low BMD is a risk factor for osteoporotic fracture. Osteoporosis is characterized by reduced bone mineral density, disrutption of bone microarchitecture, and the alteration of the amount and variety of non-collagenous proteins in bone. Osteoporotic bones are more at risk of fracture.,PTM:N- and O-glycosylated.,similarity:Belongs to the IL-6 superfamily.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Secreted .
組織表達(dá)： Produced by skeletal muscle.
科研貨號(hào)： PLA004877

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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