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LPL Monoclonal Antibody

商品貨號： PLA004916

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： LPL
蛋白名稱： Lipoprotein lipase
Human_gene_id： 4023
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4023
Human_swiss_prot_no： P06858
Human_swiss_link： http://www.uniprot.org/uniprotkb/P06858/entry
Mouse_swiss_prot_no： P11152
Mouse_swiss_link： http://www.uniprot.org/uniprot/P11152
特異性： LPL Monoclonal Antibody detects endogenous levels of LPL protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LPL; LIPD; Lipoprotein lipase; LPL
信號通路： Glycerolipid metabolism;PPAR;Alzheimer's disease;
功能： catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,disease:Defects in LPL are a cause of familial chylomicronemia [MIM:238600]; also known as hyperlipoproteinemia type I. Familial chylomicronemia is a recessive disorder usually manifesting in childhood. On a normal diet, patients often present with abdominal pain, hepatosplenomegaly, lipemia retinalis, eruptive xanthomata, and massive hypertriglyceridemia, sometimes complicated with acute pancreatitis.,disease:Defects in LPL are the cause of lipoprotein lipase deficiency (LPL deficiency) [MIM:238600]. LPL deficiency leads to hypertriglyceridemia.,function:The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). The enzyme functions in the presence of apolipoprotein C-2 on the luminal surface of vascular endothelium.,online information:Lipoprotein lipase entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,similarity:Contains 1 PLAT domain.,subunit:Homodimer. Interacts with apolipoprotein C-2. Interacts with GPIHBP1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted . Secreted, extracellular space, extracellular matrix . Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells (PubMed:27811232). Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity). .
組織表達(dá)： Detected in blood plasma (PubMed:2340307, PubMed:11893776, PubMed:12641539). Detected in milk (at protein level) (PubMed:2340307).
科研貨號： PLA004916

LPL Monoclonal Antibody

Catalog No PLA004916

Product information

發(fā)貨日期： 7
基因名稱： LPL
蛋白名稱： Lipoprotein lipase
Human_gene_id： 4023
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4023
Human_swiss_prot_no： P06858
Human_swiss_link： http://www.uniprot.org/uniprotkb/P06858/entry
Mouse_swiss_prot_no： P11152
Mouse_swiss_link： http://www.uniprot.org/uniprot/P11152
特異性： LPL Monoclonal Antibody detects endogenous levels of LPL protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： LPL; LIPD; Lipoprotein lipase; LPL
信號通路： Glycerolipid metabolism;PPAR;Alzheimer's disease;
功能： catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,disease:Defects in LPL are a cause of familial chylomicronemia [MIM:238600]; also known as hyperlipoproteinemia type I. Familial chylomicronemia is a recessive disorder usually manifesting in childhood. On a normal diet, patients often present with abdominal pain, hepatosplenomegaly, lipemia retinalis, eruptive xanthomata, and massive hypertriglyceridemia, sometimes complicated with acute pancreatitis.,disease:Defects in LPL are the cause of lipoprotein lipase deficiency (LPL deficiency) [MIM:238600]. LPL deficiency leads to hypertriglyceridemia.,function:The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). The enzyme functions in the presence of apolipoprotein C-2 on the luminal surface of vascular endothelium.,online information:Lipoprotein lipase entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,similarity:Contains 1 PLAT domain.,subunit:Homodimer. Interacts with apolipoprotein C-2. Interacts with GPIHBP1.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted . Secreted, extracellular space, extracellular matrix . Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells (PubMed:27811232). Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity). .
組織表達(dá)： Detected in blood plasma (PubMed:2340307, PubMed:11893776, PubMed:12641539). Detected in milk (at protein level) (PubMed:2340307).
科研貨號： PLA004916

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