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Lsk Monoclonal Antibody

商品貨號(hào)： PLA004918

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱： MATK
蛋白名稱： Megakaryocyte-associated tyrosine-protein kinase
Human_gene_id： 4145
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4145
Human_swiss_prot_no： P42679
Human_swiss_link： http://www.uniprot.org/uniprotkb/P42679/entry
Mouse_swiss_prot_no： P41242
Mouse_swiss_link： http://www.uniprot.org/uniprot/P41242
特異性： Lsk Monoclonal Antibody detects endogenous levels of Lsk protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： MATK; CTK; HYL; Megakaryocyte-associated tyrosine-protein kinase; CSK homologous kinase; CHK; Hematopoietic consensus tyrosine-lacking kinase; Protein kinase HYL; Tyrosine-protein kinase CTK
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Expressed in various myeloid cell lines, detected in brain and lung.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Membrane . In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
組織表達(dá)： Expressed in various myeloid cell lines, detected in brain and lung.
科研貨號(hào)： PLA004918

Lsk Monoclonal Antibody

Catalog No PLA004918

Product information

發(fā)貨日期： 7
基因名稱： MATK
蛋白名稱： Megakaryocyte-associated tyrosine-protein kinase
Human_gene_id： 4145
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4145
Human_swiss_prot_no： P42679
Human_swiss_link： http://www.uniprot.org/uniprotkb/P42679/entry
Mouse_swiss_prot_no： P41242
Mouse_swiss_link： http://www.uniprot.org/uniprot/P41242
特異性： Lsk Monoclonal Antibody detects endogenous levels of Lsk protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： MATK; CTK; HYL; Megakaryocyte-associated tyrosine-protein kinase; CSK homologous kinase; CHK; Hematopoietic consensus tyrosine-lacking kinase; Protein kinase HYL; Tyrosine-protein kinase CTK
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Expressed in various myeloid cell lines, detected in brain and lung.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Membrane . In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
組織表達(dá)： Expressed in various myeloid cell lines, detected in brain and lung.
科研貨號(hào)： PLA004918

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