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Rsk-2 Monoclonal Antibody

商品貨號： PLA005022

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： RPS6KA3
蛋白名稱： Ribosomal protein S6 kinase alpha-3
Human_gene_id： 6197
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6197
Human_swiss_prot_no： P51812
Human_swiss_link： http://www.uniprot.org/uniprotkb/P51812/entry
Mouse_swiss_prot_no： P18654
Mouse_swiss_link： http://www.uniprot.org/uniprot/P18654
特異性： Rsk-2 Monoclonal Antibody detects endogenous levels of Rsk-2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated
信號通路： Regulates Angiogenesis; Insulin Receptor; B Cell Receptor; AMPK
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,disease:Defects in RPS6KA3 are the cause of Coffin-Lowry syndrome (CLS) [MIM:303600]; an X-linked dominant disorder characterized by severe mental retardation with facial and digital dysmorphisms, and progressive skeletal deformations.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-386, as part of the activation process.,PTM:Ser-227 phosphorylation promotes Ser-386 phosphorylation and leads to basal activation. Full activation by growth factors requires additional phosphorylation on Ser-369.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity). Interacts with NFATC4.,tissue specificity:Expressed in many tissues, highest levels in skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus . Cytoplasm .
組織表達： Expressed in many tissues, highest levels in skeletal muscle.
科研貨號： PLA005022

Rsk-2 Monoclonal Antibody

Catalog No PLA005022

Product information

發(fā)貨日期： 7
基因名稱： RPS6KA3
蛋白名稱： Ribosomal protein S6 kinase alpha-3
Human_gene_id： 6197
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6197
Human_swiss_prot_no： P51812
Human_swiss_link： http://www.uniprot.org/uniprotkb/P51812/entry
Mouse_swiss_prot_no： P18654
Mouse_swiss_link： http://www.uniprot.org/uniprot/P18654
特異性： Rsk-2 Monoclonal Antibody detects endogenous levels of Rsk-2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:500 - 1:2000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated
信號通路： Regulates Angiogenesis; Insulin Receptor; B Cell Receptor; AMPK
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,disease:Defects in RPS6KA3 are the cause of Coffin-Lowry syndrome (CLS) [MIM:303600]; an X-linked dominant disorder characterized by severe mental retardation with facial and digital dysmorphisms, and progressive skeletal deformations.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-386, as part of the activation process.,PTM:Ser-227 phosphorylation promotes Ser-386 phosphorylation and leads to basal activation. Full activation by growth factors requires additional phosphorylation on Ser-369.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity). Interacts with NFATC4.,tissue specificity:Expressed in many tissues, highest levels in skeletal muscle.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Nucleus . Cytoplasm .
組織表達： Expressed in many tissues, highest levels in skeletal muscle.
科研貨號： PLA005022

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