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Rtn-3 Monoclonal Antibody

商品貨號： PLA005024

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： RTN3
蛋白名稱： Reticulon-3
Human_gene_id： 10313
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10313
Human_swiss_prot_no： O95197
Human_swiss_link： http://www.uniprot.org/uniprotkb/O95197/entry
Mouse_swiss_prot_no： Q9ES97
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9ES97
特異性： Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： RTN3; ASYIP; NSPL2; Reticulon-3; Neuroendocrine-specific protein-like 2; NSP-like protein 2; Neuroendocrine-specific protein-like II; NSP-like protein II; NSPLII
信號通路： Regulation of Microtubule Dynamics; Regulation of Actin Dynamics; SAPK_JNK; Stem cell pathway; Adherens_Junction
功能： function:May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.,induction:By endoplasmic reticulum stress (at protein level).,miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,similarity:Contains 1 reticulon domain.,subunit:Homodimer. Interacts with RTN4. Isoform 3 interacts with BACE1, BACE2, BCL2 and FADD. Interacts with Coxsackievirus A16, enterovirus 71 and poliovirus P2C proteins.,tissue specificity:Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.,
相關(guān)產(chǎn)品： YM0568,YM0567,RS0001,RS0002,YM3028,YM3029
細胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
組織表達： Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.
科研貨號： PLA005024

Rtn-3 Monoclonal Antibody

Catalog No PLA005024

Product information

發(fā)貨日期： 7
基因名稱： RTN3
蛋白名稱： Reticulon-3
Human_gene_id： 10313
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10313
Human_swiss_prot_no： O95197
Human_swiss_link： http://www.uniprot.org/uniprotkb/O95197/entry
Mouse_swiss_prot_no： Q9ES97
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9ES97
特異性： Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
純化工藝： Affinity purification
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： RTN3; ASYIP; NSPL2; Reticulon-3; Neuroendocrine-specific protein-like 2; NSP-like protein 2; Neuroendocrine-specific protein-like II; NSP-like protein II; NSPLII
信號通路： Regulation of Microtubule Dynamics; Regulation of Actin Dynamics; SAPK_JNK; Stem cell pathway; Adherens_Junction
功能： function:May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.,induction:By endoplasmic reticulum stress (at protein level).,miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,similarity:Contains 1 reticulon domain.,subunit:Homodimer. Interacts with RTN4. Isoform 3 interacts with BACE1, BACE2, BCL2 and FADD. Interacts with Coxsackievirus A16, enterovirus 71 and poliovirus P2C proteins.,tissue specificity:Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.,
相關(guān)產(chǎn)品： YM0568,YM0567,RS0001,RS0002,YM3028,YM3029
細胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
組織表達： Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.
科研貨號： PLA005024

Hunan UPT Biotechnology Co.,Ltd

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