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Syntenin-1 Monoclonal Antibody

商品貨號： PLA005156

適應(yīng) 性： 人,大鼠,狗,豬

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： SDCBP
蛋白名稱： Syntenin-1
Human_gene_id： 6386
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6386
Human_swiss_prot_no： O00560
Human_swiss_link： http://www.uniprot.org/uniprotkb/O00560/entry
Mouse_swiss_prot_no： O08992
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08992
Rat_gene_id： 83841
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83841
Rat_swiss_prot_no： Q9JI92
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9JI92
特異性： Syntenin-1 Monoclonal Antibody detects endogenous levels of Syntenin-1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： SDCBP; MDA9; SYCL; Syntenin-1; Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1
功能： function:Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.,induction:By gamma interferon in melanoma cells.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 2 PDZ (DHR) domains.,subcellular location:Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Monomer and homodimer (By similarity). Interacts with SDC1, SDC2, SDC3, SDC4, NRXN2, EPHA7, EPHB1, NF2 isoform 1, TGFA and IL5RA. Interacts with neurofascin, SDCBP2 and PTPRJ.,tissue specificity:Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.,
相關(guān)產(chǎn)品： YM1301,YM1100,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell junction, focal adhesion . Cell junction, adherens junction . Cell membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Nucleus . Melanosome . Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Secreted, extracellular exosome . Membrane raft . Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2) (PubMed:27386966). .
組織表達(dá)： Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma (at protein level) (PubMed:25893292). Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.
科研貨號： PLA005156

Syntenin-1 Monoclonal Antibody

Catalog No PLA005156

Product information

發(fā)貨日期： 7
基因名稱： SDCBP
蛋白名稱： Syntenin-1
Human_gene_id： 6386
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6386
Human_swiss_prot_no： O00560
Human_swiss_link： http://www.uniprot.org/uniprotkb/O00560/entry
Mouse_swiss_prot_no： O08992
Mouse_swiss_link： http://www.uniprot.org/uniprot/O08992
Rat_gene_id： 83841
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83841
Rat_swiss_prot_no： Q9JI92
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9JI92
特異性： Syntenin-1 Monoclonal Antibody detects endogenous levels of Syntenin-1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： WB 1:1000 - 1:2000. Not yet tested in other applications.
純化工藝： Affinity purification
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： SDCBP; MDA9; SYCL; Syntenin-1; Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1
功能： function:Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.,induction:By gamma interferon in melanoma cells.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 2 PDZ (DHR) domains.,subcellular location:Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Monomer and homodimer (By similarity). Interacts with SDC1, SDC2, SDC3, SDC4, NRXN2, EPHA7, EPHB1, NF2 isoform 1, TGFA and IL5RA. Interacts with neurofascin, SDCBP2 and PTPRJ.,tissue specificity:Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.,
相關(guān)產(chǎn)品： YM1301,YM1100,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell junction, focal adhesion . Cell junction, adherens junction . Cell membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Nucleus . Melanosome . Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Secreted, extracellular exosome . Membrane raft . Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2) (PubMed:27386966). .
組織表達(dá)： Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma (at protein level) (PubMed:25893292). Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.
科研貨號： PLA005156

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