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Eg5 mouse mAb

商品貨號(hào)： PLA005176

適應(yīng) 性： 人

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期： 7
基因名稱： kif11
Human_gene_id： 3832
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3832
Human_swiss_prot_no： P52732
Human_swiss_link： http://www.uniprot.org/uniprotkb/P52732/entry
Mouse_swiss_prot_no： Q6P9P6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q6P9P6
特異性： This antibody detects endogenous levels of Eg5 and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： wb 1:1000 icc 1:200
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： EG5;HKSP;KIF11;KIF11_HUMAN;kinesin family member 11;Kinesin like protein 1;Kinesin like spindle protein HKSP;Kinesin-like protein 1;Kinesin-like protein KIF11;Kinesin-like spindle protein HKSP;Kinesin-related motor protein Eg5;KNSL1;MCLMR;Thyroid receptor interacting protein 5;Thyroid receptor-interacting protein 5;TR-interacting protein 5; TRIP-5;TRIP5.
實(shí)測(cè)條帶： 130kD
功能： function:Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.,PTM:Phosphorylated exclusively on serine during S phase, but on both serine and Thr-926 during mitosis, so controlling the association of KIF11 with the spindle apparatus (probably during early prophase). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family. BimC subfamily.,similarity:Contains 1 kinesin-motor domain.,subunit:Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Cytoplasm, cytoskeleton, spindle pole .
組織表達(dá)： Brain,Epithelium,Lung,
科研貨號(hào)： PLA005176

Eg5 mouse mAb

Catalog No PLA005176

Product information

發(fā)貨日期： 7
基因名稱： kif11
Human_gene_id： 3832
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3832
Human_swiss_prot_no： P52732
Human_swiss_link： http://www.uniprot.org/uniprotkb/P52732/entry
Mouse_swiss_prot_no： Q6P9P6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q6P9P6
特異性： This antibody detects endogenous levels of Eg5 and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Monoclonal, Mouse
稀釋： wb 1:1000 icc 1:200
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱： EG5;HKSP;KIF11;KIF11_HUMAN;kinesin family member 11;Kinesin like protein 1;Kinesin like spindle protein HKSP;Kinesin-like protein 1;Kinesin-like protein KIF11;Kinesin-like spindle protein HKSP;Kinesin-related motor protein Eg5;KNSL1;MCLMR;Thyroid receptor interacting protein 5;Thyroid receptor-interacting protein 5;TR-interacting protein 5; TRIP-5;TRIP5.
實(shí)測(cè)條帶： 130kD
功能： function:Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.,PTM:Phosphorylated exclusively on serine during S phase, but on both serine and Thr-926 during mitosis, so controlling the association of KIF11 with the spindle apparatus (probably during early prophase). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the kinesin-like protein family. BimC subfamily.,similarity:Contains 1 kinesin-motor domain.,subunit:Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm . Cytoplasm, cytoskeleton, spindle pole .
組織表達(dá)： Brain,Epithelium,Lung,
科研貨號(hào)： PLA005176

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