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POU5F1/OCT4 mouse mAb

商品貨號(hào)： PLA005183

適應(yīng) 性： 小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

發(fā)貨日期： 7
基因名稱： pou5f1
Human_gene_id： 18999
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18999
Human_swiss_prot_no： Q01860
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q01860/entry
Mouse_swiss_prot_no： P20263
Mouse_swiss_link： http://www.uniprot.org/uniprot/P20263
特異性： This antibody detects endogenous levels of POU5F1/OCT4 and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： wb 1:1000
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： MGC22487;Oct 3;Oct 4;Oct-3;Oct-4;OCT3;Oct4;Octamer binding protein 3;Octamer binding protein 4;Octamer binding transcription factor 3;Octamer-binding protein 3;Octamer-binding protein 4;Octamer-binding transcription factor 3;OTF 3;OTF 4;OTF-3;OTF3;OTF4; PO5F1_HUMAN;POU class 5 homeobox 1;POU domain class 5 transcription factor 1;POU domain transcription factor OCT4;POU domain, class 5, transcription factor 1;POU5F1.
實(shí)測條帶： 45kD
功能： function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.,miscellaneous:Several pseudogenes of POU5F1 have been described on chromosomes 1, 3, 8, 10 and 12. 2 of them, localized in chromosomes 8 and 10, are transcribed in cancer tissues but not in normal ones and may be involved in the regulation of POU5F1 gene activity in carcinogenesis.,online information:Oct-4 entry,PTM:Sumoylation enhances the protein stability, DNA binding and transactivation activity. Sumoylation is required for enhanced YES1 expression.,similarity:Belongs to the POU transcription factor family. Class-5 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subcellular location:Expressed in a diffuse and slightly punctuate pattern.,subunit:Interacts with UBE2I.,tissue specificity:Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.,
相關(guān)產(chǎn)品： YT5777,YT3233,KA3343C,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. .
組織表達(dá)： Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
科研貨號(hào)： PLA005183

POU5F1/OCT4 mouse mAb

Catalog No PLA005183

Product information

發(fā)貨日期： 7
基因名稱： pou5f1
Human_gene_id： 18999
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18999
Human_swiss_prot_no： Q01860
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q01860/entry
Mouse_swiss_prot_no： P20263
Mouse_swiss_link： http://www.uniprot.org/uniprot/P20263
特異性： This antibody detects endogenous levels of POU5F1/OCT4 and does not cross-react with related proteins.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Monoclonal, Mouse
稀釋： wb 1:1000
純化工藝： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： MGC22487;Oct 3;Oct 4;Oct-3;Oct-4;OCT3;Oct4;Octamer binding protein 3;Octamer binding protein 4;Octamer binding transcription factor 3;Octamer-binding protein 3;Octamer-binding protein 4;Octamer-binding transcription factor 3;OTF 3;OTF 4;OTF-3;OTF3;OTF4; PO5F1_HUMAN;POU class 5 homeobox 1;POU domain class 5 transcription factor 1;POU domain transcription factor OCT4;POU domain, class 5, transcription factor 1;POU5F1.
實(shí)測條帶： 45kD
功能： function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.,miscellaneous:Several pseudogenes of POU5F1 have been described on chromosomes 1, 3, 8, 10 and 12. 2 of them, localized in chromosomes 8 and 10, are transcribed in cancer tissues but not in normal ones and may be involved in the regulation of POU5F1 gene activity in carcinogenesis.,online information:Oct-4 entry,PTM:Sumoylation enhances the protein stability, DNA binding and transactivation activity. Sumoylation is required for enhanced YES1 expression.,similarity:Belongs to the POU transcription factor family. Class-5 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subcellular location:Expressed in a diffuse and slightly punctuate pattern.,subunit:Interacts with UBE2I.,tissue specificity:Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.,
相關(guān)產(chǎn)品： YT5777,YT3233,KA3343C,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. .
組織表達(dá)： Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
科研貨號(hào)： PLA005183

Hunan UPT Biotechnology Co.,Ltd

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