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PRD16 rabbit pAb

商品貨號(hào)： PLA021562

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： PRDM16 KIAA1675 MEL1 PFM13
蛋白名稱： PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)
Human_gene_id： 63976
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=63976
Human_swiss_prot_no： Q9HAZ2
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9HAZ2/entry
Mouse_gene_id： 70673
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70673
Mouse_swiss_prot_no： A2A935
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/A2A935/entry
特異性： This antibody detects endogenous levels of PRD16 at Human, Mouse
組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000 IHC 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)
分子量： 140kD
功能： Binds DNA and functions as a transcriptional regulator . Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (By similarity). Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation (By similarity). Likely to be one of the primary histone methyltransferases along with MECOM/PRDM3 that direct cytoplasmic H3K9me1 methylation (By similarity). Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism (By similarity). Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells (By similarity). Functions as a repressor of TGF-beta signaling . ; [Isoform 4]: Binds DNA and functions as a transcriptional regulator . Functions as a repressor of TGF-beta signaling . May regulate granulocyte differentiation .
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm .
組織表達(dá)： Expressed in uterus and kidney. Expressed in both cardiomyocytes and interstitial cells.
科研貨號(hào)： PLA021562

PRD16 rabbit pAb

Catalog No PLA021562

Product information

基因名稱： PRDM16 KIAA1675 MEL1 PFM13
蛋白名稱： PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)
Human_gene_id： 63976
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=63976
Human_swiss_prot_no： Q9HAZ2
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9HAZ2/entry
Mouse_gene_id： 70673
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70673
Mouse_swiss_prot_no： A2A935
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/A2A935/entry
特異性： This antibody detects endogenous levels of PRD16 at Human, Mouse
組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500-2000 IHC 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)
分子量： 140kD
功能： Binds DNA and functions as a transcriptional regulator . Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (By similarity). Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation (By similarity). Likely to be one of the primary histone methyltransferases along with MECOM/PRDM3 that direct cytoplasmic H3K9me1 methylation (By similarity). Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism (By similarity). Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells (By similarity). Functions as a repressor of TGF-beta signaling . ; [Isoform 4]: Binds DNA and functions as a transcriptional regulator . Functions as a repressor of TGF-beta signaling . May regulate granulocyte differentiation .
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Cytoplasm .
組織表達(dá)： Expressed in uterus and kidney. Expressed in both cardiomyocytes and interstitial cells.
科研貨號(hào)： PLA021562

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