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eNOS (Phospho Ser1177) Rabbit mAb

商品貨號(hào)： PRM8788

適應(yīng) 性： 人,小鼠,大鼠

￥800元

規(guī)格：

50ul

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MSDS

說(shuō)明書(shū)

商品描述

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： NOS3/eNOS
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 133kD
MW(Observed)： 133kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Ser1177
推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0906R
特異性： eNOS (Phospho Ser1177) Monoclonal Antibody detects endogenous levels of eNOS around the phosphorylation site of Ser1177 protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TQsFS
基因名稱： NOS3
蛋白名稱： Nitric oxide synthase endothelial
別名： NOS3;Nitric oxide synthase;endothelial;Constitutive NOS;cNOS;EC-NOS;Endothelial NOS;eNOS;NOS type III;NOSIII
Organism-1： Human
基因ID-1： 4846
SwissProt-1： P29474
Organism-2： Mouse
基因ID-2： 18127
SwissProt-2： P70313
Organism-3： Rat
基因ID-3： 24600
SwissProt-3： Q62600
背景： Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
細(xì)胞定位： Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.

eNOS (Phospho Ser1177) Rabbit mAb

Catalog No PRM8788

Product information

發(fā)貨日期：現(xiàn)貨
靶點(diǎn)-Target： NOS3/eNOS
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 133kD
MW(Observed)： 133kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG, Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Ser1177
推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號(hào)： PT0906R
特異性： eNOS (Phospho Ser1177) Monoclonal Antibody detects endogenous levels of eNOS around the phosphorylation site of Ser1177 protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TQsFS
基因名稱： NOS3
蛋白名稱： Nitric oxide synthase endothelial
別名： NOS3;Nitric oxide synthase;endothelial;Constitutive NOS;cNOS;EC-NOS;Endothelial NOS;eNOS;NOS type III;NOSIII
Organism-1： Human
基因ID-1： 4846
SwissProt-1： P29474
Organism-2： Mouse
基因ID-2： 18127
SwissProt-2： P70313
Organism-3： Rat
基因ID-3： 24600
SwissProt-3： Q62600
背景： Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
細(xì)胞定位： Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.

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