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Rb (Phospho Ser780) Rabbit mAb

商品貨號： PRM8807

適應(yīng) 性： 人,小鼠,大鼠

￥7000元

規(guī)格：

500ul

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商品描述

發(fā)貨日期：現(xiàn)貨
靶點-Target： Rb
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 106kD
MW(Observed)： 106kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Ser780
推薦稀釋比： WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0992R
特異性： Rb (Phospho Ser780) Antibody detects endogenous levels of Rb protein only when phosphorylated at S780.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TLsPI
基因名稱： RB1
蛋白名稱： Retinoblastoma-associated protein
別名： RB1;Retinoblastoma-associated protein;p105-Rb;pRb;Rb;pp110
Organism-1： Human
基因ID-1： 5925
SwissProt-1： P06400
Organism-2： Mouse
基因ID-2： 19645
SwissProt-2： P13405
Organism-3： Rat
基因ID-3： 24708
SwissProt-3： P33568
背景： The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],
細(xì)胞定位： Nucleus . During keratinocyte differentiation, acetylation by KAT2B/PCAF is required for nuclear localization. .

Rb (Phospho Ser780) Rabbit mAb

Catalog No PRM8807

Product information

發(fā)貨日期：現(xiàn)貨
靶點-Target： Rb
反應(yīng)性-Reactivity：人,小鼠,大鼠
應(yīng)用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 106kD
MW(Observed)： 106kD
宿主物種-Host Species： Rabbit
同種型-Isotype： IgG,Kappa
偶聯(lián)-Conjugate： Phospho
修飾-Modification： Ser780
推薦稀釋比： WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
純化工藝： Protein A
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0992R
特異性： Rb (Phospho Ser780) Antibody detects endogenous levels of Rb protein only when phosphorylated at S780.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TLsPI
基因名稱： RB1
蛋白名稱： Retinoblastoma-associated protein
別名： RB1;Retinoblastoma-associated protein;p105-Rb;pRb;Rb;pp110
Organism-1： Human
基因ID-1： 5925
SwissProt-1： P06400
Organism-2： Mouse
基因ID-2： 19645
SwissProt-2： P13405
Organism-3： Rat
基因ID-3： 24708
SwissProt-3： P33568
背景： The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],
細(xì)胞定位： Nucleus . During keratinocyte differentiation, acetylation by KAT2B/PCAF is required for nuclear localization. .

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