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人骨肉瘤細(xì)胞(Saos-2)

￥800.00元

細(xì)胞貨號(hào)： CL0271

細(xì)胞種屬： 人源細(xì)胞系

細(xì)胞別名： SAOS-2; Saos-2; SAOS 2; Saos 2; Saos2; SaOs2; SAOS2; Sarcoma OSteogenic-2; SaOS; SAOS

發(fā)貨規(guī)格： 1×10?

供體信息： 11歲白人女性

腫瘤類型： 骨肉瘤

組織來(lái)源： 骨

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背景信息

種屬：人源細(xì)胞系
組織來(lái)源：骨
腫瘤類型：骨肉瘤
供體信息： 11歲白人女性
背景描述： Saos-2 細(xì)胞是一種骨肉瘤細(xì)胞系，來(lái)源于 11 歲白種人女性的原發(fā)性成骨肉瘤。這些細(xì)胞是研究骨肉瘤和骨生物學(xué)的廣泛認(rèn)可模型，因?yàn)樗鼈兙哂谐晒羌?xì)胞特征和產(chǎn)生骨樣細(xì)胞外基質(zhì)的能力。 Saos-2 細(xì)胞具有高水平的堿性磷酸酶活性和骨骼特異性蛋白（如骨鈣素和骨橋蛋白）的表達(dá)，可作為研究骨形成和骨肉瘤病理生理學(xué)的有效體外系統(tǒng)。它們對(duì)于研究細(xì)胞對(duì)模擬骨骼環(huán)境的各種生化刺激和機(jī)械力的反應(yīng)特別有價(jià)值。

培養(yǎng)建議

其他信息

受體表達(dá)： Epidermal growth factor (EGF), transforming growth factor beta (type 1 and type 2)
同工酶： Me-2, 1, PGM3, 1-2, PGM1, 1-2, ES-D, 2, AK-1, 1, GLO-1, 2, G6PD, B, Phenotype Frequency Product: 0.0002
致瘤性： No, The cells were not tumorigenic in immunosuppressed mice, but did form colonies in semisolid medium.
抗原表達(dá)： Blood Type B, Rh+, HLA A2, A3, Bw16, Bw47
逆轉(zhuǎn)錄酶：陰性
核型： The stemline chromosome number is hypotriploid with the modal number of 56 chromosomes per cell and the 2S component occurring at 13.2%. Over two-thirds of the chromosome complement consisted of structurally rearranged chromosomes. Most marker chromosomes had complex rearrangements. The origin of the segments composing these markers could not be identified. Of the identifiable markers, 6p+/q+, 7p+, 11p+, and 12p+ occasionally were present at 2 copies per cell. The Y chromosome was not detected in the QM stained preparation.

人骨肉瘤細(xì)胞

Catalog No CL0271

Product information

受體表達(dá)： Epidermal growth factor (EGF), transforming growth factor beta (type 1 and type 2)
同工酶： Me-2, 1, PGM3, 1-2, PGM1, 1-2, ES-D, 2, AK-1, 1, GLO-1, 2, G6PD, B, Phenotype Frequency Product: 0.0002
致瘤性： No, The cells were not tumorigenic in immunosuppressed mice, but did form colonies in semisolid medium.
抗原表達(dá)： Blood Type B, Rh+, HLA A2, A3, Bw16, Bw47
逆轉(zhuǎn)錄酶：陰性
核型： The stemline chromosome number is hypotriploid with the modal number of 56 chromosomes per cell and the 2S component occurring at 13.2%. Over two-thirds of the chromosome complement consisted of structurally rearranged chromosomes. Most marker chromosomes had complex rearrangements. The origin of the segments composing these markers could not be identified. Of the identifiable markers, 6p+/q+, 7p+, 11p+, and 12p+ occasionally were present at 2 copies per cell. The Y chromosome was not detected in the QM stained preparation.

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