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人子宮頸鱗癌細(xì)胞(SiHa)

￥800.00元

細(xì)胞貨號(hào)： CL0280

細(xì)胞種屬： 人源細(xì)胞系

細(xì)胞別名： Siha; SIHA

發(fā)貨規(guī)格： 1×10?

供體信息： 55歲亞洲女性

腫瘤類型： 人瘤病毒相關(guān)性宮頸鱗狀細(xì)胞癌

組織來源： 子宮頸

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背景信息

種屬：人源細(xì)胞系
組織來源：子宮頸
腫瘤類型：人瘤病毒相關(guān)性宮頸鱗狀細(xì)胞癌
供體信息： 55歲亞洲女性
背景描述： SiHa細(xì)胞是一種人宮頸鱗狀細(xì)胞癌細(xì)胞系，幾十年來已廣泛用于研究。它們是從一名 55 歲的日本女性鱗狀細(xì)胞癌患者的原發(fā)性子宮活檢片段中分離出來的。由于其獨(dú)特的遺傳特征，該細(xì)胞系對(duì)研究宮頸癌和其他相關(guān)疾病的研究人員非常感興趣。

培養(yǎng)建議

其他信息

同工酶： AK-1,1；ES-D, 2；G6PD, B；GLO-I, 2；Me-2, 1；PGM1, 1；PGM3, 1
基因表達(dá)： p53+; pRB+
致瘤性： Yes, in nude mice; forms poorly differentiated epidermoid carcinoma (grade III)
核型： modal number = 69; range = 51 to 72.This is a hypertriploid human cell line with the modal chromosome number of 71, occurring in 24% of cells. Most cells had the chromosome numbers distributed between 69 and 72. Polyploid cells occurred at 7.6%. Fifteen or more marker chromosomes were common to most cells. Among them are dup(2) (q22q31) and del(2) (q31) which probably resulted from the balanced translocation between two N2s. Most cells had two copies of del(2). M2 is an A3-sized acrocentric. M13 is a minute submetacentric with 1-3 copies per cell. Origins of both M2 and M13 are not identified. There were two copies of normal X chromosomes. N2 was absent and probably was replaced by dup(2) and del(2).

人子宮頸鱗癌細(xì)胞

Catalog No CL0280

Product information

同工酶： AK-1,1；ES-D, 2；G6PD, B；GLO-I, 2；Me-2, 1；PGM1, 1；PGM3, 1
基因表達(dá)： p53+; pRB+
致瘤性： Yes, in nude mice; forms poorly differentiated epidermoid carcinoma (grade III)
核型： modal number = 69; range = 51 to 72.This is a hypertriploid human cell line with the modal chromosome number of 71, occurring in 24% of cells. Most cells had the chromosome numbers distributed between 69 and 72. Polyploid cells occurred at 7.6%. Fifteen or more marker chromosomes were common to most cells. Among them are dup(2) (q22q31) and del(2) (q31) which probably resulted from the balanced translocation between two N2s. Most cells had two copies of del(2). M2 is an A3-sized acrocentric. M13 is a minute submetacentric with 1-3 copies per cell. Origins of both M2 and M13 are not identified. There were two copies of normal X chromosomes. N2 was absent and probably was replaced by dup(2) and del(2).

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